List of stupidly abstract moments so far (Note: SPOILER ALERT):
I'm going to try to respond to these in turn in all seriousness.
1) Anna hiding under the bed - when you click on the bed, Anna says that she can't hide there because the Monster will find her. She does not specify that what she means is hiding INSIDE THE COVERS. This led to a 'wtfstuck' moment because I assumed I could not hide under the bed.
-Perhaps this was obscure, and I guess I got lucky because I found "Under the bed" before I even considered just clicking on "bed". Still, it doesn't hurt to look around more.
2) Telling Emma about the time - needlessly complicated. It should just be a case of putting 'clock' into a conversation. I did eventually figure out what I had to do first, by randomly clicking on everything.
-This was a bit hard for me too, at first, but that's part of the STM system. This will be my reply to a couple of the other point.
3) Finding the boss' first name - needlessly complicated
-Is it? It's common for log-in names to be first initial+last name, plus you would need to log in as the boss eventually anyway. It's more of a slap-yourself-since-it's-so-obvious.
4) I've got to put a mirror inside a newspaper? Really? Do I need to even explain this one? This is so bloody abstract as to be ridiculous. Again the only way you'd figure this out is by random clicking everywhere.
-... this is abstract? How so? Honestly, I'd like to know why you say this.
5) There is no hint or clue that Bennet's wallet should be clicked on to produce two new items.
-The clue is to examine the object, which gives them to you. Something you might try after Bennet's sarcastic comment of sticking his wallet in the newspaper stand.
6) The wing mirror of the car is really difficult to spot unless you're specifically looking for it. And since random clicking is how to solve this puzzle, it doesn't help. Again, clicking on car produces 'not relevant' responses so it's not logical to assume that there is a part of the car that IS relevant. Needlessly complicated.
-No, it's more of a "pixel hunt" issue. And bigger than some others I've played.
7) Talking to Saul about the valve - why can't I just ask him directly for a wrench? What the hell? Needlessly complicated.
-Part of the STM system.
8 ) Having to remind Saul about his story in order to get the wrench - needlessly complicated and reliant upon an absolutely absurd feat of memory - picking out the obscure fact that Saul mentioned using it earlier. Needlessly complicated and one of the worst so far.
-I kind of liked this trick, as it requires you to pay attention to the conversation. (Admittedly, I had spoiled this for myself by watching David demo it on a webshow before release.)
9) Using the pipe on the rusty pipe - very unintuitive due to the fact that Ed doesn't specify WHY he can't use the pipe. Logic: use the pipe to replace the broken one. Click. Can't do it. Why not? No idea, the game doesn't tell me. Solution: back to random clicking.
-Um, how? You need to remove the rusted pipe before you can put in the new pipe.
10) The 'Pi' message. Lovely little nerd easter egg, but what about people that don't know the symbol for Pi? They are truly screwed, aren't they?
-Nope! Did you check out that panel in the upper-left of the lab? It's got a calculator, with a convenient Pi button on it. Most people would know pi offhand, but not beyond 3.14, so having it there for the 4th digit is pretty good.
11) After you get all four characters - I've explored quite a bit and have no clue how to proceed. Got a vague idea about getting the FTTN number from the Hospital database but can't get Emma to go away. Can't put pressure on Tortoise so can't get his info to access the police database. No clues from any characters or items in game to tell me where to go. Solution: back to random clicking.
-Solution: ask the other people what THEY think. The other characters are you in-game help.
12) Can't use mainframe until you talk to Emma about it using the right click into menu system - why doesn't this conversation flow naturally from the point where you attempt to use the mainframe? Needlessly complicated.
-I don't think it's needlessly complicated, but I'm not sure why Anna wouldn't have worked just as well (except that it's a very restricted system).
13) Using the ultra sonograph on the you know what - seriously? How is this even remotely obvious? I have no idea what a ultra sonograph is, it's a pretty huge leap in logic to realise that I have to use this with the you know what.
-Did you pay attention when Anna picked up the device? "We have some fun with these to look through all kinds of stuff", or something similar. There's your hint.
14) Couldn't use the USB PW cracker because Johnsen's computer has a flap over the USB slot, but the error msg doesn't say 'it's covered by a flap' it just says 'it doesn't fit' which results in another wtfstuck moment. Needlessly complicated?
-Or you need to look a little closer before you just drag-and-drop.
15) Distract Johnsen by asking him about the copy room - how am I supposed to know in advance that I can distract him by doing this?
-Trial and error, admittedly. Examining the copy room gives a little bit of a hint.
16) Using the credit card to open the tech room door - wow. I don't know what to say.
-Using a credit card to jimmy open locks is an old trick. I forgot this one, too.
17) That bloody magnet puzzle, not even needlessly complicated just virtually impossible. In the end I was just flicking the mouse up and down the screen in fury and it somehow passed the choke point.
-You mean the locker or the logic to take the magnet? Because taking the magnet was not obvious for me. The maze, though, was just a bit of trial and error.
So from that list, a lot of the problems were tied to the structure of the puzzle system, you not looking around enough or skipping over the hint. So perhaps the game isn't for you, but I don't think it was unfair in general.